While some industry experts and analysts believe that DeFi will eventually take over CeFi, it is too early to be sure about such claims. In this article, we have discussed some of the key differences and similarities between CeFi and DeFi. Bitcoin introduced the world to a whole new set of blockchain-based financial applications. CeFi (Centralized Finance) has been around since the time Bitcoin first emerged. However, a new trend has come into view in the form of DeFi (Decentralized Finance), which has garnered a lot of attention over the last year.